Bioinformatics at Addgene

From the beginning, one of Addgene’s goals was to ensure the scientific community obtained high-quality data for our DNA-based reagents. Not only do we extract as much information as possible from depositing laboratories and associated publications, but our quality control (QC) standards have evolved over the years to keep up with the latest tools. In Addgene’s early days, we would ‘spot-check’ critical regions of plasmids deposited with us via Sanger sequencing, while more recently we have moved to full plasmid sequencing at our facility using Illumina MiSeq Next Generation Sequencing (NGS) technology.

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