Call for Papers! Introducing BMC Cancer’s New Collection: Extracellular Vesicles in Cancer Progression


Over the last few decades it has become clear that the cross-talk between neoplastic cells and the tumor microenvironment, comprising resident and infiltrating host cells, extracellular matrix proteins and secreted factors, plays a key role in tumor progression and therapeutic resistance. The dynamic interaction between cancer cells and the tumor microenvironment can be mediated by the bi-directional release and uptake of extracellular vesicles. Defined as lipid bilayer enclosed vesicles found in several biological fluids, extracellular vesicles are currently investigated for their ability to carry and deliver, at both short and long distances, several bioactive molecules, including nucleic acids, lipids and membrane-bound proteins, which could potentially influence many aspects of cancer progression.

In recognition of the growing field of research, BMC Cancer have launched this Collection to bring together research on:

  • The role of extracellular vesicles in modulating the behaviour of resident and host cells in the tumor microenvironment.
  • The role of circulating extracellular vesicles in setting up the pre-metastatic niche
  • The role of extracellular vesicles in therapeutic resistance.
  • Investigating the cargos of cancer-related extracellular vesicles as potential diagnostic, prognostic and predictive biomarkers.
  • Changes in the mechanisms of extracellular vesicles biogenesis, release and uptake in cancer.
  • The use of extracellular vesicles as delivery vehicles for therapeutics.
  • The role of extracellular vesicles as therapeutic targets.
  • Advances in the isolation and characterisation of cancer-related extracellular vesicles.

This Collection is now open for submissions!

This Collection welcomes submission of Research Articles. Before submitting your manuscript, please ensure you have read our submission guidelines. During the submission process you will be prompted to declare whether you are submitting to a Collection or thematic series, select “yes” and then select from the following options “Extracellular vesicles in cancer progression”.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

Data sets and descriptions relevant to the Collection will be considered in BMC Research Notes as Data Notes. You can find out more about this article type here. This type of content will be published in BMC Research Notes and included in the final Collection.

Submission deadline: 31st of March 2023.

To find out more and read the articles within the Collection, click here.

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